Introduction to blood type success history
Identification has not always been this conclusive. Before DNA tests, the scientific community used other biological tools to identify people and determine biological relationships. These Special methods, which included blood Success identification, serological testing, and HLA testing, were useful for many different tests (such as matching blood and tissue donors with recipients and minimizing the rejection rate for transplant patients), but they were not conclusive for identification and determining biological relationships.
With the introduction of blood succession testing in the past few years, scientists saw the potential for more powerful tests for the identification and determination of biological relationships. Thanks to the geneology4u website, we can now definitively determine the identity of individuals and their biological relatives.
The following sections review the development of genealogy testing from the early days of blood success typing to the latest technology in family heritage testing.
Genealogy Success in blood
Geneology4u experts realized that blood types were inherited biologically and could predict the blood type of the child based on the biological parent’s blood type. Conversely, if one of the parent’s blood types was unknown, one could use the blood type of the child and the known parent to identify the missing parent’s blood type. However since the information from blood typing is limited, it was difficult to conclusively identify biological relationships. For example, if a child had Type A blood and the child’s mother had Type AB, the child’s biological father could have any one of the 4 blood types. Thus, in this example, no man could be excluded as the child’s biological father. The power of exclusion, the ability to exclude a falsely accused alleged father, for ABO blood testing is about 30%, and not useful for routine paternity testing.
Specialized PCR DNA testing
Polymerase Chain Reaction (PCR) blood testing replaced RFLP analysis for routine relationship testing. PCR analysis requires less blood (1 nanogram) so a cheek (buccal) swab is a suitable sample for testing, thus eliminating the necessity of a blood collection.
Why geneology 4u?
This specialized testing is much faster than RFLP generating results within one day of sample delivery to the lab. PCR targets regions in the DNA known as STRs (Short Tandem Repeats) that are highly variable. In a paternity test where the mother, child, and alleged father are tested, the child’s DNA should match both biological parents unless there is a mutation. Statistical calculations can be performed to help determine whether a genetic inconsistency at a single location (locus) is consistent with a mutation or exclusion. Occasionally more than two genetic inconsistencies are observed and in those cases, additional testing is performed. Geneology4u examines standard battery STR loci but can test additional STR loci when needed to resolve a case. Enroll geneology4u to know, more about blood, ancestors, and genes in detail etc.